Task:Respiratory system paper Translation,edit and proofreading
Selected Source Languages:English.Background. Respiratory syncytial virus (RSV) pneumonia after hematopoietic cell transplant (HCT) is associated with severe morbidity. Although RSV RNA has been detected in serum from patients with RSV lower respiratory disease (LRD) after HCT, the association with clinical outcomes has not been well established in multivariable models. Additionally, the role of antiviral treatment in HCT recipients has not been previously analyzed in multivariable models.
Methods. We retrospectively identified HCT recipients with virologically confirmed RSV LRD and tested stored plasma/serum samples by quantitative reverse transcription polymerase chain reaction for RSV RNA. Risk factors for RSV RNA detection and the impact of RSV RNA in serum and antiviral therapy on outcomes were analyzed using multivariable Cox models.
Target Deliverable Languages:Chinese.背景：造血干细胞移植（HCT）后的呼吸道合胞病毒（RSV）肺炎与严重疾病发病率有关。虽然RSV RNA已在HCT后RSV下呼吸道疾病（LRD）患者血清中检测出，但与临床治疗结果的关系尚未建立完善的多变量模型。此外，对HCT受体抗病毒治疗的作用以前还没有在多变量模型中分析。
方法：我们回顾性地鉴定由病毒学证实RSV LRD的HCT受体，和通过定量逆转录聚合酶链反应测试储存血浆/血清样品的RSV RNA。RSV RNA检出的风险因素，以及血清中RSV RNA和抗病毒治疗对结果的影响用多因素Cox模型进行了分析。
Should you have any demands in Medical and life science translation and localization,please feel free to get in touch with our Account Manager:Robin.email@example.com